Paclitaxel Injection is used to treat:
• as first therapy (after initial surgery in combination with the platinum-containing medicine cisplatin).
• after standard platinum-containing medicines have been tried but did not work.
• as first therapy for advanced disease or disease which has spread to other parts of the body (metastatic disease). Paclitaxel Injection is either combined with an anthracycline (e.g. doxorubicin) or with a medicine called trastuzumab (for patients for whom anthracycline is not suitable and whose cancer cells have a protein on their surface called HER 2, see package leaflet of trastuzumab).
• after initial surgery following treatment with anthracycline and cyclophosphamide (AC) as an additional treatment.
• as a second-line treatment for patients who have not responded to standard treatments using anthracyclines, or for whom such treatment should not be used.
Advanced non-small-cell lung cancer:
• in combination with cisplatin, when surgery and/or radiation therapy aren’t suitable.
AIDS-related Kaposi's sarcoma:
• where another treatment (i.e. liposomal anthracyclines) has been tried but did not work.